Non-toxic building materials are gaining significant attention as awareness of indoor air quality, health, and environmental sustainability grows. Homeowners, architects, and construction professionals are increasingly seeking alternatives to conventional products that emit volatile organic compounds (VOCs) and other hazardous chemicals. Embracing non-toxic materials not only promotes well-being for building occupants but also contributes to a healthier planet by reducing pollution and supporting ethical manufacturing practices. This exploration delves into what defines non-toxic building materials, their health benefits, leading material options, and guidance for their effective integration into building projects.